Editorial: Immune Complexes in Disease Pathology

Editorial: Immune Complexes in Disease Pathology

Specialty section: This article was submitted to Alloimmunity and Transplantation, a section of the journal Frontiers in Immunology Foreign and modified self-antigens bind to natural IgM to form immune complexes (ICs). This facilitates the instructive phase of immunity, which programs immune response to generate class-switched high affinity antibodies required for IC formation, resulting in pat...

Circulating Immune Complexes in Atherosclerotic Vascular Disease

Circulating immune complexes in lung disease.

Circulating Immune Complexes in Lung Disease H ypersensitivity lung diseases, of which allergic aspergillosis is a prototype, are an immunologic curiosity. Organisms usually of little virulence grow in plugs of airway mucus. These organisms are protected by the mucous matrix which seems to serve as an adjuvant. The ensuing brisk immunologic response is ineffective in clearing the bronchial tree...

Diagnostic Pathology – Editorial

At the end of this year our open access journal Diagnostic Pathology does exist for about nine months. It has been designed to cover all aspects of diagnostic surgical pathology or tissue based diagnosis and related medical and biological disciplines. An editorial board of well – known experts assures the scientific quality of the submitted articles. In the beginning we had to learn how to hand...

Circulating immune complexes and disease activity in Crohn's disease.

Circulating immune complexes were determined in 59 consecutive patients with Crohn's disease and 100 blood donors by a double method based on the inhibition of the agglutinating activity of CIq and/or rheumatoid factor on the IgG-coated polystyrene particles. In patients, the incidence of positive immune complexes was 63% and 61% at first testing, 85% and 78% at subsequent determinations; there...